VUMC Islet Procurement & Analysis Core

IPA Core procedures are currently on hiatus due to the COVID-19 pandemic. Please contact Marcela Brissova, Anastasia Coldren, or Heather Durai with questions. We hope to be up and running again soon!


Overview of Services

The Islet Procurement and Analysis Core (IPA Core) is a core of the Vanderbilt Diabetes Research and Training Center (DRTC). Pancreatic islet biology, development, and function are major DRTC research areas with investigators studying a variety of islet-related processes ranging from intracellular signaling, immunology of type 1 diabetes, islet-enriched transcription factors, to islet transplantation. The objective of the core is to facilitate research of DRTC-affiliated investigators by providing high quality, well-characterized mouse pancreatic islets.


Mouse Islet Isolation
Islet Perifusion
Static Islet Incubation
Islet Culture
Islet RNA Isolation
Whole Slide Scanning & Image Analysis
Assistance with Human Islets
Assistance with experimental design



*Acknowledgements for Islet Procurement & Analysis Core*
Please remember to acknowledge the Islet Procurement & Analysis Core when submitting publications. The Islet Procurement & Analysis Core is supported by the Vanderbilt Diabetes Research and Training Center (P60 DK020593).


Marcela Brissova (Tel. 615-936-1729), PhD, Core Director

Anastasia Coldren (Tel. 615-936-2858), BS, Senior Research Specialist

Heather Durai (Tel. 615-875-8486), BS, Senior Research Specialist

Shaojun Mei, (Tel. 615-875-8661), MD, Senior Research Specialist

Corey Davis, (Tel. 615-936-2902), MS, Research Assistant

Dannielle Gibson, (Tel. 615-936-9118), BS, Research Assistant

Alisa Escue (Tel. 615-322-2397), Core Administrator

Location and hours of operation

Hours Location

Islet Procedures: M - F 8 am - 4:30 pm  

Slide Scanning: 24/7

8445C MRB IV

8434 MRB IV

Links and Resources



Name Role Phone Email Location
Marcela Brissova
Core Director
8435G MRB4
Anastasia Coldren
Scientific Research Core facility Coordinator
7475 MRB4
Alisa Escue
Core Administrator
807E Light Hall
Heather Durai
Sr. Research Specialist
8445 MRB4
Shaojun Mei
Research Assistant
7475 MRB4

Available Equipment and Resources

Name Price
Scan Scope CS View calendar
Scan Scope FL View calendar
Indica Labs Image Analysis Workstation View calendar