VUMC Institute of Imaging Science (VUIIS) - Human Imaging

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VUIIS Human Imaging Core

Overview of Services

What we can do for you

The Human Imaging Core operates a diverse set of imaging resources for structural and functional imaging, including MR, PET/CT, peripheral CT, OCT, and NIRS scanners. We also support magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) protocol development, functional MRI (fMRI) experimental design, subject preparation, structural and functional image analysis, and training on image analysis techniques and tools.

 

Description

The Human Imaging Core is dedicated to the application of advanced and prototypical MRI methods to study specific organ systems of the human body such as: nervous (central and peripheral), muscular-skeletal, cardio-pulmonary, and integumentary systems. Additionally, many ongoing projects focus on development and validation of novel MRI biomarkers for the assessment of numerous diseases (e.g. cancer, multiple sclerosis, amyotrophic lateral sclerosis, epilepsy, concussion), conditions (cognitive impairment, learning disability), and normal function (activation of the human brain, sensitivity to pain). Specifically, our researchers are working on MRI methods sensitive to 1) tissue anisotropy, 2) tissue composition, 3) tissue metabolism, and 4) tissue function. 

 

Resources

 

All of our resources are operated as full-time research instruments and not as clinical facilities.

 

Two 3 Tesla MRI Scanners

Both systems have a 60 cm bore diameter and Philips peripheral pulse, respiratory and cardiac gating capabilities as well as audio/visual presentation equipment available.

  • 3TA was decommissioned on April 30, 2018 for preparation of the installation of a state-of-the-art 3T Philips Elition whole-body imager/spectrometer.
  • 3TB: Philips Ingenia CX MR whole-body imager/spectrometer. This is a state-of-the-art system with a fully digital signal chain from coil to reconstructer. The system has excellent gradient performance (80 mT/m gradient strength, 200T/m/s slew-rate), 32 independent digital receiver channels, and dual-channel excitation.

 

7 Tesla MRI Scanner

60 cm bore diameter Philips Achieva whole-body MR imager/spectrometer. The scanner has a moving bed and an intercom system for communication between investigators and subjects. The system has the same software, pulse-programming environment, and pulse sequences as current 3 T Philips scanners. The 7 T system has Philips peripheral pulse, respiratory and cardiac gating capabilities as well as audio/visual presentation equipment available.

 

PET/CT

The Philips Vereos PET/CT is a whole-body scanner with Digital Photon Counting (DPC) technology, which offers enhanced image quality and quantitative accuracy compared to analog time-of-flight performance.

 

Mock MRI Scanner

This laboratory consists of an inactive scanner identical to that of our research systems, and includes an audio system for playing reproductions of scanner noises. This laboratory is designed to introduce patients, particularly children, to the environment in the actual scanner, and to screen for claustrophobia.

 

Near Infrared Optical Tomography (NIRS)

Oxyhemoglobin, deoxyhemoglobin and total hemoglobin concentration changes can be recorded using the portable 24-channel Hitachi ETG-4000 Near Infra-Red Optical Tomography system.

 

Optical Coherence Tomography (OCT)

SPECTRALIS OCT is a non-invasive ophthalmic multimodality imaging instrument which uses near-infrared light to visualize and measure the thickness of retinal layers. Real time tracking of the retinal structures can be used to detect early signs of eye conditions, diabetes, and coronary events. Click here for a video!

 

High Resolution peripheral Quantitative Computed Tomography (HRpQCT) 

High resolution peripheral quantitative CT with the Scanco XtremeCT II (XCT II) allows bone density measurement and 3D quantification of the microarchitecture of the bone at the distal tibia and radius of humans.

Please note, a contract with Mereo BioPharma must be obtained prior to use of this resource. For more information, please contact us at vuiis.hi.studyreview@vanderbilt.edu.

 

 

Location and Hours of Operation 

Physical Location

Mailing Address

Hours

Map

1161 21st Ave South

MCN AA-1105

Nashville, TN 37232-2310

Hours vary by resource

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