VUMC Institute of Imaging Science (VUIIS) - Center for Small Animal Imaging

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Overview of Services

What we can do for you

 

Our center has in vivo and ex vivo imaging capabilities of small animals and tissue samples via magnetic resonance imaging, x-ray/X-ray CT, Positron emission (PET) and single photon emission and bioluminesence/fluorescence imaging.

We provide training for users on ultrasound and optical imaging, and provide expert instrument operators for other modalities. We also provide expert support/training for data/image analysis.

 

 

Description

 

The Center for Small Animal Imaging (CSAI) is a comprehensive resource of state-of-the art biomedical imaging instruments spanning a wide range of modalities, including MRI, X-ray/X-ray CT, PET, SPECT, ultrasound, bioluminescence and fluorescence. These instruments provide a means of quantitative and radiological evaluation of pre-clinical models of disease, including cancers and numerous neurological and musculoskeletal disorders. The CSAI also serves as a primary laboratory for many VUIIS faculty who are active in the development of imaging technologies, including instrument design, molecular imaging innovation, and novel imaging characterization of tissue micro-anatomy and function.

 

 

Resources

 

MRI

  • 4.7T (31 cm bore) Varian with dual channel, multinuclear for rats, guinea pigs and rabbits
  • 7.0T (16 cm bore) Bruker with single channel for rat and mouse
  • 9.4T (21 cm bore) Varian with Dual channel, multinuclear for rat and mouse
  • 15.2T (11cm bore) Bruker BioSpec with cryoprobe for mice

PET, SPECT, and CT

  • Siemens Inveon PET/CT for rodent and specimen imaging
  • Siemens MicroPET Focus 220 for small-animal and non-human primate
  • Bioscan NanoSPECT SPECT/CT for nuclear imaging of small animals)
  • Faxitron digital X-ray imaging system
  • Scanco microCT40 for high resolution 3D x-ray computed tomography of bone, soft tissues, and synthetic materials with a maximum specimen diameter of 36 mm and isotropic voxel size of 6 um – 80 um
  • Scanco microCT50 for high resolution 3D x-ray computed tomography of bone, soft tissues, and synthetic materials with a maximum specimen diameter of 50 mm and isotropic voxel size of 0.5 um – 200 um
  • Scanco vivaCT80 for in vivo x-ray computed tomography imaging of small animals with a maximum diameter of 90 mm and isotropic voxel size of 5 um – 360 um

Ultrasound, Optical

  • PerkinElmer IVIS Spectrum bioluminescent and fluorescent imaging system
  • Two CRI Maestro optical imaging systems for in vivo fluorescence
  • Visen FMT: Quantitative optical tomography in small animals
  • Li-Cor Pearl for small animal optical imaging
  • VisualSonics high-resolution ultrasound system

Fully Equipped Animal Preparation, Operation and Monitoring Laboratory

Leadership


Director, Center for Small Animal Imaging:  
Mark Does

Manager, Center for Small Animal Imaging: Jarrod True

 

Director, Small Animal Nuclear Imaging: Todd Peterson

 

For general questions or assistance:  VUIIS.CSAI@vumc.org

Location and hours of operation

Hours Location

Monday-Friday

8:00 a.m.-6:00 p.m                   

AA-1105 Medical Center North   

Links and Resources

  1. Core Home Page
  2. New Project Request
  3. Instrument Descriptions